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10-20-2009, 06:41 PM
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Senior Member
Join Date: Feb 2009
Posts: 191
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Affective disorders: Antidepressant action through gene regulation
A recent paper in the Journal of Neuroscience has shown that inhibitors of histone deacetylases (HDACs) — enzymes that affect the acetylation status of histones and regulate the remodelling of chromatin — have antidepressant actions.Although currently used antidepressants rapidly modulate monoaminergic systems in
Read More from Nature Neuroscience... |
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